All of us looked into serum folic acidity (FA) amounts within sufferers along with erection dysfunction (ED) and/or early climax (PE). Going on a fast serum examples had been from forty two sufferers along with ERECTILE DYSFUNCTION, thirty six along with PE, twenty five ERECTILE DYSFUNCTION sufferers along with PE, as well as thirty wholesome males; the actual imply intravaginal climax latency period (IELT) had been calculated throughout a four weeks baseline time period. Amounts of intercourse the body’s hormones (follicle-stimulating hormone, luteinizing hormone, complete testosterone), homocysteine (Hcys), as well as FA had been calculated utilizing chemiluminescent immunoassays. The actual lovemaking features associated with PE sufferers as well as regular manage males had been examined while using Chinese language Catalog associated with Early Climax (CIPE). The actual abridged Worldwide Catalog associated with Erection Function-5 (IIEF-5) set of questions had been accustomed to evaluate erection high quality with regard to ERECTILE DYSFUNCTION sufferers as well as with regard to regular regulates. Serum FA levels had been reduced ERECTILE DYSFUNCTION (7. sixty one ± 3. ninety-seven ng ml -1 ), PE (9. thirty seven ± 3. forty ng ml -1 ), as well as ED/PE (8. 84 ± four. twenty-eight ng ml -1 ) sufferers compared to within wholesome males (12. twenty three ± 5. seventy six ng ml -1. G 0. 05). There have been good correlations in between serum FA levels as well as CIPE ratings (r = 0. 530, G < 0. 01), IIEF-5 ratings (r = 0. 589, G < 0. 01), as well as IELT (r = 0. 445, G < 0. 01); damaging correlations along with Hcys levels (r = - 0. 487, G < 0. 01) had been present in just about all individuals. These types of results demonstrated a powerful romantic relationship in between serum FA amounts as well as lovemaking disorder, perhaps because of an impact associated with FA about the metabolic process associated with nitric oxide, Hcys, as well as 5-hydroxytryptamine.